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What to think when only free light chain ratio is abnormally high?
Blood Cancers & Disorders | Last Active: Dec 11, 2025 | Replies (24)Comment receiving replies
@georgiagurl I am going to weigh in here and agree with @wesleym and @pmm that an actual doctor visit with diagnostic results are in order.
I will however say that treatment, if I am reading those numbers correctly (I am not an MD) cannot wait forever.
I say this because of the recent event with high light chains and my husbands kidneys.
I would add that a call to the current doctors office to find out if this appointment is with the doctor might be helpful.
This in addition to a second opinion at the cancer center.
I know this is a crazy ride but try to stay in the fight until you get all the results you need. It is amazing how much better we felt once we knew all the particulars of my husbands myeloma, and the plan moving forward.
Do you have your appointment yet at the cancer center?
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@auntieoakley I see that you are also a volunteer mentor and that is an awesome thing for you to do. I don't have my appt yet at the cancer center. They are supposed to call me by today to set up. I agree the light chains are very high and that they can impact the kidneys but my egfr is at 76 so they are above the concerning number of 60. I keep thinking that since I only have one of the R-ISS myeloma events that I must be smoldering mm (which the Bone Marrow pathologist said in his report). I also know there is much debate over when a smm patient should begin treatment. I think the second opinion at the Cancer center should help weigh the importance of each test. As an aside, I worked in the insurance industry for over 27 years and I thought we had a million acronyms. But the acronyms I have encountered in researching this disease far surpasses my old industry!