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ADT, maybe not? Anyone opted out of ADT?
Prostate Cancer | Last Active: Jun 29 9:00am | Replies (162)Comment receiving replies
I have never heard of the Arterra Test and the decipher test. Is this something new? I had to stop Lupron after 4 months or thought I would die because of very severe side effects. I had 44 radiation treatments along with the Lupron.
My doctor never suggested anything but Lupron and did not tell me much about the side effects. I have absolutely no libido or errections five months after treatments and my PSA < 0.1 and testosterone is < 9 at 1 month and 4 months after stopping Lupron. At 5 months after stopping Lupron I still have all the side effects but they seem to be very slowly decreasing except for joint pain.
Replies to "I have never heard of the Arterra Test and the decipher test. Is this something new?..."
@pesquallie Orgovyx is oral, much better tolerated and can be stopped, with symptoms gone within a week.
But how would YOU know if your doc never mentioned it? I did happen to know about it so I asked about it and my RO totally agreed. SE’s were minimal in my case, but a few men still have problems with it.
Phil
@pesquallie
Not familiar with Arterra Test. The Decipher has been around for some time. Mayo Jacksonville R/O recommended I take it back in January of 2023.
The Decipher test is something I personally suggest as it really had an impact on my personal experience with PC. I was originally diagnosed at intermediate risk PC. The Decipher test came back low risk.
It changed my treatment plan from radiation with hormone treatments to radiation only. I also believe it can really help more accurately define your risk level much better than Gleason Scores.
I have read many many posters experience with hormone treatments. I cannot comment on hormone treatments as have no personal experience with them. But from what I read over many many posts that everyone is different it how they respond to the hormone treatments and clearly that what one will post as their experience does not mean you will mirror it.
@pesquallie
The ArteraAI test has been available for two years and was approved by the FDA in August 2025.
We talked about the decipher test repeatedly in this forum. Did you really mean to include it when you said you Never heard of it?
Some medical centers use it as a standard to decide some aspects of the treatment for patients.
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@pesquallie
Both the ArteraAI and Decipher Tests are relatively new. The decipher was starting to be heavily used in June 2025, the ArteraAI test in August 2025. These are tests that really have Been needed, but have just recently been heavily used.
The UCSF prostate cancer system uses it for almost all of their patients.
Then there is the Polaris test which has been around since 2010. Similar way to predict reoccurrence.
Lupron can be tough to deal with For some people. The thing is, it does extend lives. Hopefully, you can find something that works for you.