@laura1970 New to these threads so Im not sure if your reply was for me or previous person - but for me, no other meds, no underlying conditions (knocking on wood!). Follow up - had 3 horrible days S/M/T - jittery, fearful, anxiety and intrusive thoughts off the charts (not like me, I'm very calm, positive, level-headed, happy. optimistic type) so something is definitely not right. Went to my Dr again yesterday (he's beyond amazing) and we looked at and did rule outs of everything including my worse fears (needing a brain scan) and he's pretty certain since the only thing different in my life over the past year is the addition of HRT, that's the culprit and to lower my Estradiol patch in hopes it's better dosing and balance for my now lowered 35mg Progesterone, and my being so petite. Im starting new 0.375 patch tomorrow and praying I can go back to my normal, happy, strong, positive, optimistic life!