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My platelet count has increased after a year on Hydroxyurea (HU)
Blood Cancers & Disorders | Last Active: Jan 23 6:11pm | Replies (37)Comment receiving replies
I have been taking HU for almost 9 months now. Platelets were at 1200 in March 2025 with diagnosis of ET. My dose of HU has fluctuated over the months, starting at 500 mg daily, to 1000 mg MWF, reduced to 500 daily when platelets got to 314, then 500/ 3 days on MWF but platelets went up to 446 and now 500 mg 4 days/week and platelets are rising again at 489. So my magic number might be 500 mg daily. I am on the watch and wait schedule. My goal is to take as little as possible of HU. I tried Fosomax with it for Osteoporosis but bone and joint pain got worse. I dropped Fosomax and am trying to cover Osteoporosis naturally with exercise and weight lifting as well as clean eating. The roller coaster is crazy and now a breast lump. I am trying to cope. Biopsy coming up.
Replies to "I have been taking HU for almost 9 months now. Platelets were at 1200 in March..."
@mumblipeg From all of us on Hydroxyurea, this is a common occurrence. I stayed at 850, with dose changes and now steady dose, I’m going up and down between 350-450. I’d hold off and let them play with the meds again being this number isn’t really dangerous currently. Are you getting a Bone marrow biopsy soley because your platelets are creeping up? Do some research. Ask questions. Mainly will your treatment change from the results. Good luck!
@mumblipeg
Praying for your biopsy results and that your platelets count will stabilize. Hugs sent your way!
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@mumblipeg
So sorry you are dealing with so much I’ve been on hydroxy since 2018 and it’s kept my platelets in a good place. Jakafi was my doc’s preferred choice.. as it’s supposed to be most beneficial.. but I had too many side effects Maybe it’s an option for you. Hope
your biopsy results gives you good news. In my prayers