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Hi, osteopatient2026.
Evenity is pretty amazing. It builds bone the most rapidly of any of the medications.
Where I see Tymlos and Forteo as having a distinct advantage is that they "remodel" bone. Sclerostin is necessary for the cells that breakdown bone (osteoclasts) to form, and blocks the production of the bone building cells (osteoblasts). Evenity slows the production of osteoclasts and increases the production of osteoblasts
Osteoclasts are attracted to areas of bone that are fissured, older bone that has lost density and vascularity. With Evenity that older a-vascularized bone isn't removed. Evenity-bone is heavier without the canalization that typifies less dense remodeled bone. Remodeled bone is formed by a balance between damaged bone removal and new bone growth.
I completely agree with the information in your post. Bone density is the way we measure strength and may be the greatest contributor to strength. Flexibility and vascularity are the measurement where Tymlos and Forteo exceed the advantages of Evenity.

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Replies to "Hi, osteopatient2026. Evenity is pretty amazing. It builds bone the most rapidly of any of the..."

@gently as with any med, it also depends on what other health issues you have and what other meds you need to take…that’s where docs . NPs and pharmacists can help…also, these Mayo Connect boards can be very helpful about what it’s like to actually live these things.

@gently
That’s an excellent and very good explanation…
I’m seeing a lot of reports as of late with a shift towards the Evenity approach… slow the loss but not completely and build bone hopefully trabecular and cortical. Lots of new research trying to fast track the Evenity method. It’s the first so more tweaked versions to come.
Supplements can be good I guess but our systems are designed to only use so much of each vitamin and mineral. The enzymes, amino acids and digestive system calls upon so much from whole body to metabolize, create the right recipe and send it where it’s needed.
Truly a miracle…

@gently I read that with Evenity, you are at risk os cardiac issues and or a stroke.