Hi, Cyndy,

I, too had alot of hair loss on lefluonmide. I stopped it, and went back to methotrexate. Up to 50% of people on lefluonmide have hair loss. I also had lost 15 pounds in a short period of time. I went and saw a dermatologist, Antonella Tosti, at the University of Miami that specializes in hair & nails. She's written textbooks on hair and nails. She told me I had chronic telogen effluvium because of rapid weight loss and then gave me the statistic on lefluonmide. She told me to take 3 mg of melatonin at bedtime, and come back in 6 mos. When I went back my hair had grown (remember I had 2 things going on). I experience hair loss from RA, but not methotrexate.