Radiation or not after surgery for endometrial cancer?

@round2 many thanks

@ffr Doc said “maybe” the two are related. Also, I used Estradiol vaginal suppositories after anal cancer for 6 years to help heal the effects of radiation, but now they want me to change to a non-hormone cream because of possible recurrence of endometrial cancer from using Estradiol. Hmmm…. Hope that makes sense — I think chemo-brain is kicking in a bit!

@round2 I did not have cancer before I was diagnosed with endometrial cancer (endometrioid adenocarcinoma, FIGO Grade 1, Stage 1a) in 2019. I had been using estradiol for about 6 years prior to that diagnosis. It's a confusing controversy however my gynecologist and the providers at Mayo's Menopause and Sexual Health Clinic told me that minute amounts of estrogen are absorbed in the bloodstream when administered vaginally - which is essentially as if you are rubbing it on the back of your hand called "transdermal". Still, since my cancer diagnosis my doctors have told me I can no longer use estradiol. I guess it's why take the chance? The estradiol worked very well for me. I now use a vaginal lubricant two times a week that contains hyaluronic acid. You can purchase these products over-the-counter.

Which non-hormonal cream does your doctor recommend?

Had brachytherapy 5 treatments to the vaginal cuff following surgery. Recommended because it is a likely place for recurrence.
Have Stage 1a endometrial carcinoma however it is Clear Cell. I had zero problems with the radiation. Nothing.
The radiologist oncologist also has follows me every 3 months. I'm 15 months postop so I have a way to go...clear cell is aggressive and I have the p53 gene. Been told I have done everything I can do at this point. Have the brachytherapy- be cautious but don't skip it if you're worried about side effects. Good luck.

Hi,

I’m in the same situation and need to decide if I go ahead with radiation or not. Diagnosed with endometrial cancer figo grade 1, stage 1A2 after surgery completed on 09.26.2025. Met with radiology dr. and he said its my decision if I choose to do 3 brachytherapy sessions or only the regular follow-up, Did anybody regret doing the brachytherapy? If there is a recurrence in the future, what are the implications of having done brachytherapy already? Thank you

@naturegirl5 I use revaree plus-but I don't have sex anymore- this i hyaluronic acid- keeps the area moist and non itchy- I had brachytherapy- diagnosed with stage 1a-2 serous papillary endometrial- two separate opinions said brachytherapy would protect the vaginal cuff from recurrence-so far so good- diagnosed in May 2017/ Also had 6 rounds carboplatin and taxol

@jar1591927 I had serous papillary- which is very serious as well. Stage 1a-2 had two different opinions. Same protocol carboplatin and taxol then Brachytherapy. Diagnosed May 2017- so far so good.

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On Mon, Dec 8, 2025 at 4:16 AM, jan< jar729@yahoo.com> wrote: 👍

I'm still recovering from hystrectomy and will probably have Brachytherapy 3 treatments in January. Just to give me peace of mind that if I have a re-occurence in the future I won't have regrets not having the treatments which might have prevented it.