All of my symptoms point to sero negative rheumatoid arthritis (or also called palindromic rheumatism). I have had swollen and painful hands and wrists, swollen feet, sometimes in my shoulders too. First flare up was in 2012 and lasted about a month. Totally went away and I had no idea what it was then. Then 2nd flare up was this past May and it lasted for 8 weeks. Then the 3rd flare up started mid-October of this fall. That's when I was diagnosed. Another symptom that happened with 2nd and 3rd flare up was pain in my chest when breathing in deeply. Spent a day in emerg a week ago and I suspected it was pleurisy and was right. Got a cat scan and found out there is fluid build up on the bottom of my lungs and on the left side. T

Very frustrated with my rheumatologist because they never answer their phones and take forever to call you back after leaving a message. After this episode of being in emerg and finding out I have pleurisy which is caused by PR, he just put me back on 5ml of prednisone. Hopefully that helps ... when it comes to my lungs I don't want to mess with this. I don't want to be on prednisone for too long but my blood test show that my inflammation is very high.

I have been on Plaquenil since the beginning of November and that can take a while to start to help.