Recovery of testosterone and side effects after stopping ORGOVYX

Posted by mikejf @mikejf, Dec 1 1:19pm

Diagnosed 2018 with Stage four Metastasized PC. Had 4 rounds of chemo then Lupron injections for about a year and then prescribed ORGOVYX. Have been only on ORGOVYX for 5-6 years. Recent PET scans (2025) show no active cancer anywhere. My oncologist recommended stopping ORGOVYX and monitoring PSA and Testosterone level every 3 months. It’s been a few weeks with no ADT. Questions: Has anyone had diarrhea as a side effect of stopping ADT and how long before Tetosterone returns along with muscle gain etc. etc. thank you

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Profile picture for kujhawk1978 @kujhawk1978

Ok...

You asked "Has anyone had diarrhea as a side effect of stopping ADT and how long before Tetosterone returns along with muscle gain etc. etc. thank you.

The first question, no.

The 2nd question, well, it varies.

My experience, albeit a study of one, after triplet and later doublet therapy, my T "recovered" to 400+ in the first six months.

Why? Neither I or my medical team can say answer that question.

I was 61 when I came off triplet therapy, 67 when I came off doublet.

Perhaps as sone of the literature suggests and my medical team doesn't disagree, exercise played a role.

How much, what kind...not sure there is an answer. MY, study of one, most days I go to the gym, 45-60 minutes on the bike, resistance training and swimming.

There are days I ride outside, 35-45 miles.

Our vacations are pretty active, lots of hiking, I do like to ski in the winter.

Then there are the usual domestic ones, walking our dog, yard work, household chores.

Kevin

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