Can't decide which drug to take.

@osteopatient2026 That's Very Helpful to learn. I thought it was mostly dehydration causing nausea. I'll check it out. Yes, lots to learn! A long journey . . .

@victoria93
Sometimes changing time of injection is more to do with your calcium intake. Again no calcium 1 1/2 hours before and none 4 hours after. Many side effects are due to dehydration and what you consume before and after. There is a definite reason that your whole endocrine system and sympathetic nervous system gets overloaded along with your kidneys. Sounds like you are in the right track. As always get your doctor’s advice. Some doctors just don’t know about many of the things you are learning here…in fairness there is so much to know.

Very important to contact a Endocrinologist and their Clinical Pharmacist. The pharmacist can sit down with you and go over all the meds for Osteoporosis. They can help determine which one is best for you
Some of the meds are contraindicated if you have certain health conditions. This will help you decide.

@victoria93
When you sign in to Tymlos website you can make an appointment with a clinician…they will call you and set up a time on your phone to go through the whole thing. We had a wonderful women Lillian.
The reason I mentioned starting full dose was that is the drug companies recommended dose. It was a relief to know if there was any side effects (less than 5-10% of people have anything they can’t deal with) you can always back down. You might surprised…I’m a real wimp with needles …I pass out at the sight of them. You can do it.

@osteopatient2026 Thanks for that info about clinician. I've seen their video and it was excellent, clear and helpful. I'm not too much of a wimp w needles but have little confidence about "doing it wrong"! A personality failing of mine from way back! Your encouragement is balm to the soul!

@victoria93
Here is a list I put together to help me…hope it helps you …
It’s true very few have only minor side effects….
Possible side effects…
Lightheadedness / Low Blood Pressure
When:
Usually within 10–30 minutes after the injection
Most common during the first week
Often lessens over time
Watch for:
Dizziness
Feeling faint
Brief drop in BP (e.g., 90/60 → 80/55 for 10–20 min)
How to manage:
Sit down immediately after injecting
Inject before bedtime
Stay hydrated
Don’t drive for 30 minutes after
When to call the doctor:
If you faint
If dizziness lasts >1 hour
If it becomes worse week-to-week rather than improving
Testing needed:
No formal test
Optional: home BP checks for the first week
2. Fast Heart Rate (Palpitations)
When:
Usually within 5–20 minutes after injection
Lasts 5–30 minutes
Very common in first week
Watch for:
Heart pounding
Heart racing
When to call doctor:
If fast heart rate lasts >1 hour
If new chest pain
If you have underlying heart disease
Testing:
No routine tests
Rarely, your doctor may order an EKG if symptoms are persistent
3. Nausea
When:
First 1–2 weeks
Usually mild and temporary
Watch for:
Nausea
Upset stomach
How to reduce:
Watch calcium intake
Inject with a small snack
Avoid large meals near injection
Try nighttime dosing
Testing:
None needed unless unable to keep fluids down
4. Injection-Site Redness, Swelling, or Soreness
When:
Anytime during treatment
Often worse when changing technique or injecting too close to the navel
Watch for:
Redness the size of a dime or quarter
Slight swelling
Tenderness
When to worry:
Redness spreading >2–3 inches
Heat, pus, fever → could be infection (rare)
Treatment:
Cold compress
Rotate injection sites
Let alcohol swab dry fully before injecting
Do NOT re-use needles
Testing:
None needed
Less Common Side Effects (But Important to Know)
5. High Calcium (rare with Tymlos — much less than Forteo)
Tymlos rarely causes high blood calcium, but your doctor still monitors it.
Watch for:
Nausea
Constipation
Increased thirst
More urination
Muscle aches
Testing:
Blood calcium test at baseline
Repeat if symptoms appear
Your doctor may test at 1–3 months if you are high risk or on calcium supplements
6. Kidney stones (rare)
Because Tymlos can mildly raise calcium levels in some people.
Watch for:
Sharp flank pain
Blood in urine
Testing:
Urinalysis only if symptoms occur
Aside from making a nice comfy place to relax.

@osteopatient2026 I generally take my calcium at breakfast and plan to do the injection in the
early evening, so no conflict there. But keeping up hydrating is always a problem considering my aged bladder that likes to work overtime so I tend to cut back before bed. Guess I'll have to change that plan.

@osteopatient2026 WOW! You are amazing to do this for me. Thank you SO MUCH! I'm going to print it out and keep it for reference, since I won't remember all that, especially w anxiety riding high. Explain about why calcium intake so important, what does the drug do because of calcium? I have so much to learn!

@osteopatient2026 So far I've been to 2 endocrinologists, both incredibly pushy, nearly bullying, and recommending Evenity followed by Prolia. I wondered if they're being paid by the drug company. I explained about the 2 TIA's but they blew past that info as if it was unimportant, so I lost trust in them. It takes over an hour's drive to get to them on a nasty fast highway crawling w trucks, and I have to be driven because of my bad eyes, so a price to pay. Wasted money both times, except I did learn to avoid Evenity - for me! Important lesson.

@victoria93
Hi again…helping you helps me as well.
Because Tymlos “calls upon” your calcium stores…there is a “load” on your system much in the way when you are tired at the end of a long day and your stores are depleted somewhat. (It is more than just calcium and I don’t know enough as my husband knows more)
Your kidneys and everything else are being called on to keep going which sometimes can make you feel not so good. Again most people do fine. I got reassurance from others here when I started and from the lady from Tymlos who has walked hundreds if not more people through this. Once your system adjusts you should be fine. Again everyone is different but I was worried I would be one that didn’t do so well. So far so good for me almost 4 weeks in.