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Seeking your thoughts on PSA of .1 on Orgovyx and Nubeqa
Prostate Cancer | Last Active: 4 days ago | Replies (27)Comment receiving replies
@xahnegrey40 Yes, he is staying on the Orgovyx + Nubeqa. He hasn’t had any chemo or radiation just the prostatectomy. Because of numerous positive lymph nodes the plan was to have chemo in the next few months but the doc seems to have lost the urgency for chemo. I guess that’s a good sign? The doc did mention he believed the hormones would work for several years and in that time the other systemic treatments would only get better perhaps skipping chemo and going straight to a radioligand which targets the PC cells better. Thank you for your comments I found them comforting.
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@ucla2025
13 years after my prostate cancer diagnosis I started on Orgovyx and Nubeqa. I’ve been on it for three years now and my PSA has stayed undetectable at < .1. You keep saying it’s at .1, Is it actually < .1?
The thing is hormone therapy does not eliminate the cancer. It will reduce it in size and stop it from growing and spreading. After six years of my being on hormone therapy, I did get a metastasis in the bone on my back, Previous CT scans had showed it might be there, but it was not significant. Had that zapped with SBRT radiation when I stopped Zytiga.. As long as you don’t have too many metastasis, they can zap them. It’s when you have more than about five that they like to use chemo. I know one guy that had a dozen of them in his bones zapped, A few at a time, and that resolved his problems for a while. Metastasis in the bone are not the end of the line. They even have radium 223 to treat multiple bone metastasis.
My history just for information, 8.5 years on hormone therapy
In 2010 I was 62 and a biopsy showed Gleason 3+4. My father died of prostate cancer and he had radiation so I decided to have surgery. After surgery they told me it was a Gleason 4+3. It was only stage two. 3.5 Years later it came back, I had a Lupron shot 2 months before 8+ weeks of radiation. 2 1/2 years later it came back and I went on Lupron. I became castrate resistant 2.5 years later and added biclautamide. 1.25 years later went on Zytiga, which kept my PSA down for 2 1/2 years. After some AFIB Issues I switched over to Nubeqa. The last 25 months I’ve been undetectable. I became stage four about six years ago, had a metastasis on my spine zapped 2 years ago. I did not find out I was BRCA2 Until five years ago. That’s why it keeps coming back, I’ve had four reoccurrences.