@lacraig1 So are they saying you need to have chemo to “obliterate” the micro mets that can’t be seen on the scan? Your scan was clear, right?
My husband had many visible positive nodes on his PSMA scan so they wanted to do chemo soon. Now it seems there is no rush. We were also initially warned about it getting into the bones. We were on the “obliterate” plan until a few weeks ago. Agree there seems to be no right answer. So confusing. The plan right now is to keep checking every six weeks for changes. I am going to ask for another PSMA in the new year so we can see the effects of the hormones on the lymph nodes. Even then, we won’t know anything about the micrometastatic cells that don’t show up. I feel like the hormones aren’t enough as obviously the PC is in his bloodstream.

@lacraig1
As long as you don’t have too many metastasis, they can zap them, even if they are in the bones. It’s when you have more than about five that they like to use chemo. I know one guy that had a dozen of them in his bones zapped, A few at a time, and that resolved his problems for a while. Metastasis in the bone are not the end of the line. They even have radium 223 to treat multiple bone metastasis.