@dribbles
You are going to get a lot of post about antibiotics. What one person gets or does should not suggest what you should do. Only your doctors have your complete medical and mental health history.

I don't see any post from those that did come down with infection from a transrectal. If you read their stories they definitely would not have transrectal again. Several past posters had serious time and recovery. I am not sure how many are out there got infections with transperineally. You can still get an infection if done transperineally but it is very low.

Urologist doing biopsies recommend antibiotics for a reason. The chance of infection is there and antibiotics are a preventive measure. For me doing something preventive is much more important that having to take massive antibiotics after a post procedure with an infection. But that is me and not trying to say do this or that.

My urologist (Mayo Jacksonville) gave me a 2% chance of infection if done transrectal. If done transperineally such a low number not given. However, with any surgery there is chance of infection and thus the antibiotics suggestion.

Most urologist and R/Os (doing markers and Space/Oar, biopsies) will do a smear to determine the specific type of antibiotic for you.

Your decision though. Talk to your medical doctors about your concerns.