Hi, I’m following this and would also be interested in your thoughts on biologics. I was diagnosed with ulcerative colitis 2 years ago and was in remission a few months on mesalamine and developed drug induced acute pancreatitis as a result of that. Prior to that, I had been taking Canasa and Uceris (budesonide) - both rectally because there is less systemic absorption. Prior to the UC, I had been in excellent health. My GI doc has been pushing Entyvio and I’m terrified of the side effects of biologics. I have been trying to find and talk to people that have taken them, as these flares are getting worse.... Thanks for any input, and good luck to you!