Thank you to both mikeydc2008 and to marybird. I still have not taken Jardiance. All of your comments are very helpful. My nephrologist has now decided that Jardiance would not be a good option for me because I was on another (less expensive) SGLT-2 inhibitor drug, and my creatinine level increased. She had me discontinue it, and my creatinine level decreased. So, she is no longer recommending a SGLT-2 inhibitor drug, due to my kidney issues. However, I see my cardiologist this week. Since I have HFpEF, he wants me on an SGLT-2. Reading the side effects mentioned here, I may err on the side of caution and not take it. By the way, I asked my primary his opinion, he has a relative who also passed away due to necrotizing fasciitis, described by Marybird. Without another echo, I don't have any idea how bad my diastolic dysfunction is (a few months ago it was diagnosed as Grade 3 Severe. So, I am still in a bit of a quandary - I highly appreciate everyone who has responded with their experiences.