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Trying to decide between IMRT with boost or SBRT with boost. GG2, Decipher .36, Arterra 4.3. Clean PSMA, confined to prostate. Mostly 3+4. One 3+3, a couple of 4+3. T2B. My RO doesn't seem to want to do SBRT. Has given me a solid reason but is really pushing the IMRT. I'd prefer SBRT just for convenience, sake all other things being equal. Any thoughts on this from anyone.

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Replies to "Trying to decide between IMRT with boost or SBRT with boost. GG2, Decipher .36, Arterra 4.3...."

@frw
You might want to take a look at the PCRI conference on YouTube 11/1/25. Skip through to where the radiation oncologist spends a lot of time talking about SBRT radiation. Because of a higher dose of radiation, it kills the cells more efficiently. He discusses it a lot with great detail.

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SBRT is now considered a standard of care option for prostate cancer in the United States

• SBRT is supported by multiple high-level studies:
• HYPO-RT-PC
• PACE-B
• UCLA-Led General Consortium Study
• UCLA-Led SHARP Consortium (high risk disease)

My brother was a Gleason 4+3. At 77 he had five treatments of SBRT at UCSF. He’s now 80 and his PSA has been pretty stable. I know a lot of other people that have had SBRT and had similar results.

@frw
what was the reason your RO gave for not using SBRT?

@frw
I had SBRT (5 treatments) with 6 months of ADT at a "center of excellence" in the northeast. Unfortunately, I had several side effects- urinary retention (resulted in an ER visit and three weeks with a foley, followed by self-catheterization), rectal bleeding etc. I'm four years post treatment and still having problems.
Has anyone mentioned brachytherapy? It can deliver a higher dose and not impact surrounding tissues.