I have just finished weaning myself of Effexor. I was on 150 mg, then switched to 75 mg for about a month, then 37.5 mg for another month while taking a starting dose of Mirtazapine for sleep. Of course I had the usual brain zaps and still do from time to time, but it is wonderful to have feelings in my sexual organs again. I am more subject to frustration and anger but my partner tolerates it. I haven't experienced anxiety like before and I took CBD oil daily while reducing Effexor. I meditate daily and practice living in the present moment, which is so very important.