Prescribed Tymlos after Evenity

Posted by hollygs @hollygs, Nov 17, 2024

I completed a one year course of Evenity in September 2023. I switched endocrinologists afterwards, and he prescribed Fosamax after a brief discussion. I contacted the doctor who had prescribed Evenity, and he advised that I come to the office. He prescribed Tymlos, which I have now been on for 8 months. I changed my medical insurance to Medicare, and the doctor who prescribed both Evenity and Tymlos doesn't take it. I went back to the doctor who prescribed Fosamax after Evenity and he freaked out and said Tymlos is NEVER given after Evenity. His colleague in the same office concurred. He then ordered Prolia. I contacted the manufacturers of both Evenity and Tymlos, and they were very considerate and informed me that to their knowledge, there have been no studies about using Tymlos after Evenity. I am currently on a wait list for a new endocrinologist. I have a history of vertebral fractures and I need dental work, and I don't want to be on Prolia. I can finish the remaining months of Tymlos, or switch to Fosamax and wait and see what the new endocrinologist recommends. Needless to say, the situation is not ideal as I'm winging it. That being said, I know that treatment for osteoporosis is complicated and we patients have to be our own advocates and do a lot of research. I'm not opposed to that, but I'm not finding any information for protocols that have a progression of Evenity to Tymlos and then? If anyone has any information to share, I'd really appreciate it.

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Profile picture for sunny65 @sunny65

Hi @windyshores ,
Actually , my endocrinologist called me today. He is concerned to stop Evenity now because insurance might cancel coverage on Evenity and then don’t approve Tymlos, because they both anabolic . He still insists that my increased pain is due to fractures not a side effect of Evenity. I am thinking to call insurance and ask if they would approve Tymlos in the middle of my treatment. Besides he worries that insurance might not approve Tymlos even I finish all 12 months of Evenity for the same reason. He said that I might have to go on Prolia after Evenity which I completely was against but again he stated that Prolia rarely causes back pain. Not sure if our conversation was that productive . I am going for my MRI next week and if there are no new fractures, I am going to call him back and maybe ask again. All I know that pain I am going through is not sustainable for a long time and something needs to be done.

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@sunny65 well its listed on all these osteo drugs depending on what site your on some sites have more sude effects listed. Drugs .Com has them all for all drugs . I won't do prolia have too many common side effects already on the list not wanting to make any of them worse or get additional. Not till I got one foot in grave will I ever do prolia. My aunt on it for 8 years or 10 maybe has had 3 frx on it. HIP leg and arm.

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Profile picture for awfultruth @awfultruth

@hollygs Hi, I've never heard of producing abnormal bone. Could you direct me to the source of that information? And, I'd love to hear your results after a year on Tymlos.

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@awfultruth id call abnormal bone what bisphos do ; they dont let our old bone break down to receive new bone so its scrappy old brittle bone it goes over with prob scrappy old bone too because they are not bone builders. Like a holey linoleum floor under a quarter inch plywood sooner or later its going to break.

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