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Amy long-term survivors in our group?

Breast Cancer | Last Active: Dec 29, 2025 | Replies (45)

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I'm sorry to hear about your recurrence. I would guess that this is the biggest fear we have - will it come back? When? Where? I see all the percentages of 5 year survival, 10 year survival ... I see that and think it doesn't make me feel comfortable knowing that sometimes that means recurrence, treatment and survival. Has anyone seen any information on clinical research/trials of medications/treatments that seek out dormant/sleeper cancer cells and destroy them? I would love to hear any info about this.

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Replies to "I'm sorry to hear about your recurrence. I would guess that this is the biggest fear..."

@reeno I read that researchers are conducting clinical trials that use existing oral drugs, such as hydroxychloroquine and everolimus, to target and eliminate dormant breast cancer cells. These "sleeper cells" are resistant to traditional chemotherapy and can reactivate years later, leading to recurrence. Early trial results are promising, showing that the drugs can clear dormant cells and significantly lower recurrence rates in participants.

@reeno there are multiple research teams looking at all kinds of ways to to prevent recurrence. I am not sure they are all funded but I had an opportunity to be in the room with many researchers and listen to them speak.
I feel very blessed to have been at this meeting as a guest and hear all of them talk quite passionately about their chosen paths in breast cancer research.
The hard reality is many will not be funded or underfunded, and many will not pan out originally, but these are dedicated people and this is how research moves forward.
We are all terrified of the recurrence unless it happens, then I believe most of us just do what is necessary and keep moving forward. Have you had a recurrence?

@reeno
I was recently diagnosed with breast cancer on Nov 11 and had the cryoablation procedure done on Dec 17 instead of a lumpectomy. No surgery and no anesthesia! Since I don't plan on taking any drugs with horrible side effects, I have done a lot of research looking into natural compounds against cancer stem cells and bioactive foods to stop cancer stem cell re-growth. Also, Dr. Young Kim, Ph.D, at the National Cancer Institute and is an expert in nutrition as it relates to cancer prevention.