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High PSA, but MRI is negative. Biopsy or Not?

Prostate Cancer | Last Active: 7 hours ago | Replies (55)

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@beachflyer
Can I asked. When you had your biopsies where they done MRI/Fusion? Or since MRI was not showing suspicious areas they did a ultrasound? Is not a ultrasound a lot less informative than a MRI?

When you had your MRI did they use a contrast? The contrast gives a much clearer and defined picture of the prostate.

In my case I had MRI done with contrast. Did not find tumors/lesions just suspicious areas. Many many PCs are at the cellular level meaning only the cells are different than normal cells not that you have a tumor or lesion. This was my case I had not tumors or lesions.

I am not sure the hesitation of biopsies as they really do reveal if you have PC. With the caveat that need to be done correctly and enough areas of prostate to get a good report.

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Replies to "@beachflyer Can I asked. When you had your biopsies where they done MRI/Fusion? Or since MRI..."

@jc76
Hi jc76

The original scan was a contrasting MRI. I think it came out pirads 1 or 2. So with poor MRI scan the doctor planned to use ultrasound to guide. Once on the table he inserts the wand and sees no shadows, nothing. Seeing nothing on the ultrasound scan , he actually said “this is an unnecessary procedure” and suggested we stop. I responded something is really wrong (due to hematuria) and we are here so lets do it. At this point the samples were essentially taken at random with no guidance.
I am glad I did the biopsy for sure. I understand biopsies can miss things however …nothing is fool proof. The surgeon (Dr Ahlering ) at UCI told me that 8 -10 % of us can get scan negative PC and it can go undetected until is is quite advanced.