@maggieb246

I could not find a link to the supposed research.

@maggieb246
I read what it says about the “key research”. It isnt on OsteoFrax itself but research on the ingredients. So no real third party testing on the supplement itself. That is not adequate testing.

@maggieb246 the ingredients in osteofrax are showing some very interesting results https://www.sciencedirect.com/science/article/abs/pii/S0753332216314019
https://pubmed.ncbi.nlm.nih.gov/22850441/
https://pubmed.ncbi.nlm.nih.gov/35523116/

@maggieb246 Here are a couple links from Google Scholar to studies, the first is of cissus quadrengularis. It was a review of published research, and their take was the total samples were 354 people, and most of the studies has indication of bias:
https://link.springer.com/article/10.1186/s12906-025-04995-8
The second was a review of 50 years of studies of dalbergia sissoo (common names sheesham or Indian Rosewood). A handful of those studies explored the osteogenic (bone enhancing) properties, and only one of these, involved humans (30women for 12 months)
https://academic.oup.com/jpp/article/75/4/482/7057817
Here is a link to that study where women were given 300 MG of the herb twice a day for 12 months, along with daily calcium and vitamin D. There was no control group:
https://journals.lww.com/jomh/fulltext/2019/10010/a_clinical_study_of_a_standardized_extract_of.8.aspx
Given the extremely small samples, the sparsely of carefully constucted studies, and the huge price of the supplement, I personally would pass.

We also do not know the potential side effects of these unregulated supplements. Keep in mind that Osteoporosis medications are subject to 3 phases of regulated testing and documentation of all side effects. Products like Osteofrax have not been subjected to any of this.

What is your hesitation to trying drugs from your doctor?