← Return to Has anyone had experience with Jakafi?
DiscussionHas anyone had experience with Jakafi?
Blood Cancers & Disorders | Last Active: Dec 29, 2025 | Replies (94)Comment receiving replies
Replies to "Has anyone had an excacerbation of squamous cell cancer after using Hyderabad or jackafi?"
@baygirl80 I was on Jakafi for 8-9 years before my ET converted to secondary myelofibrosis. In the latter years I was on the Jakafi, I did develop 5 squamous cells that were removed with MOHS surgery each time. I was not very cautious in the sun before I developed the first squamous cell but did start using sunscreen and wearing appropriate clothing/hats thereafter, You should have a full body exam by a dermatologist or their qualified NP/PA every 6 months if you are taking Jakafi or any of the JAK inhibitors.
@baygirl80 I was diagnosed with squamous cell after 5 years on Jakifi. it was removed and am more careful in sun. last checkup all clear.
Connect

@baygirl80 Yes!! When my Jakafi dosage was increased from 10 to 15 mg my skin cancer incidents got worse. I had them before, but with the increase in Jakafi I had three separate ones removed from my right hand in 8 months. My hematologist said Jakafi encourages the cell growth, so I went back to 10 mg and am back to my normal having a few things frozen every year.