Neutropenia and thrombocytopenia 100+ days after autologous Stem cell

Posted by bizzylizzy @bizzylizzy, 1 day ago

Hi
I was diagnosed in Oct 24 with AITL (angioimmunoblastic T cell lymphoma) and had 6 rounds of R CHOP, got a complete response and then had a autologous stem cell transplant in March 25. My blood levels started lifting and all looked good 40-50 days out. Bone marrow biopsy showed everything looked in order, and PET scan showed no sign of cancer. BUT, then for strange reason my neutrophils keep disappearing and unless I inject with GCSF 2x week, they get to be around 0.2 (or less), AND platelets are sitting around 50-70. Drs are thinking it is autoimmune given bone marrow biopsy looks good and no sign of cancer. My RBC are in normal range. I had Rituximab and IVIG during my chemo to try and bring platelets/neutrophils up and it did not respond to it. Dr not keen to do it again.
Has anyone else had this? It is a bit unusual. They are watching it, and waiting. is there any danger with staying on GCSF injections long long term?
Thanks
Liz

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coloradored | @coloradored | 19 hours ago

Hi, Liz. I too had an autologous stem cell transplant for AITL in Feb. I had CHOP prior to the conditioning chemo in preparation for the transplant. I have not experienced what you are currently going through, but wonder whether a platelet infusion would be helpful at this point. Please let me know how you're doing. It is rare to find another person on this site who was diagnosed with AITL.

bizzylizzy | @bizzylizzy | 13 hours ago

Where I live the rule is platelet transfusions when you go under 20. I have had lots in the past when I was going through chemo. They don’t seem too bothered at 50.
I feel great after my stem cell and if it wasn’t for blood tests I wouldn’t know there was a problem. Lots to be grateful for …
@coloradoed do they say you are in remission?
They think I am.
Although I sometime do think that a hallmark of this cancer is thrombocytopenia and neutropenia. Hmmm???
🤷‍♀️

coloradored | @coloradored | 3 hours ago

I am 9 months out from my stem cell transplant & have not been told I am in remission at this point. I have a PET scan on Dec 3rd.

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