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Medical marijuana and restless leg syndrome

Posted by kilnaboy74 @kilnaboy74, Aug 9, 2021

Are there any credible unbiased studies available that address the short and long term affects of medical marijuana on sleep issues, including Restless Leg Syndrome? My RLS is severe. Prescription pramipexole no longer controlled my RLS. Adding THC and CBD oil in the past 2 weeks has completely eliminated my RLS for the first time in 12 years. Will it do so long term and will I experience side effects? Any research is welcomed.

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dmulvane | @dmulvane | Nov 16, 2025
In reply to @wrandytaylor "I’m a male , 71 years old and I’ve dealt with this since I was a..." + (show)
Profile picture for wrandytaylor @wrandytaylor

I’m a male , 71 years old and I’ve dealt with this since I was a kid. I could be the poster child for RLS. The only time I remember not having problems is when I was smoking a lot of pot. Currently I am taking Ropinirole er 6 mil tablets. Clonazepam and 10 mil methadone and I still cannot go to sleep without a battle at night. It’s really getting to me as two of the meds have depression as side effects and then the sleep situation causes depression as well. I haven’t smoked pit for a long time but I am desperate. Any help would be appreciated. I mean I kick walls when it starts acting up in my feet and arms as well. Like I said ….i could be the poster boy for RLS. Doctors love me because they’re pill pushers. I need help.

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wendyh | @wendyh | Nov 16, 2025

Consult with the sleep medicine department at Mayo. They are worldwide experts in RLS and you may find that your meds are no longer the drugs of choice. Good luck. It’s not an easy road to switch but it can get better!

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kcmogal | @kcmogal | Nov 16, 2025
In reply to @dmulvane "@wrandytaylor" + (show)

Age 70, and I too have suffered with restless legs for countless years. Have taken Ropinrole for 25 years, though symptoms are still severe. It has been suggested I take gabapentin and eventually eliminate the Ropinrole.

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supip | @supip | Nov 17, 2025

Magnesium glycinate works for me. Years ago my pcp prescribed clonazepam. It worked, but I now realize it caused multiple other medical problems including chest pain that sent me to the ER many times only to be sent home after nothing was found. Withdrawal from clonazepam and other benzodiazepines can be pretty horrible.

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