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Anyone have cancer with unknown primary?

Cancer | Last Active: Dec 22, 2025 | Replies (224)

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@sheridonaldson yes m sister just received that diagnosis, she is in a lot of pain but is starting chemo Wednesday. They have no idea where is is located but they said it is stage 4 and has math a year to live. I am devastated..so we will start chemo Wednesday oh and her legs are so swollen she can hardly walk, we are 71 but have been in great health until this…we are twins so now I am worried. Anyone else had their legs blown up like up like this

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Replies to "@sheridonaldson yes m sister just received that diagnosis, she is in a lot of pain but..."

@jmw184, how is your sister doing? Did her oncologist and symptom management nurse help to resolve the swelling legs?

@jmw184 I am sorry to hear about your twin sister! I have not been in a lot of pain due to the cancer, but I look pregnant from the room the tumors take up in my abdomen. I was given 2.5 years to live but have blown past that so take heart. Have never had swollen legs; could they be from something else?

@jmw184 ~ I'm sorry that your sister has been diagnosed with this awful disease. I had gone to the ER with swollen legs that were so heavy, I could hardly lift them. My legs & lungs were full of blood clots. While in the hospital, (26 days!) trying to figure out why a healty 58 yo woman would have these clots, they found stage 4 cancer of unknown primary. They have done every scan, biopsy, CT, PET, etc. possible, and still no official diagnosis. Yes the prognosis sucks but please try to remember that she's been diagnosed early and lots of things can happen between now & then. Hugs.