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Smoldering Myeloma: Coping with the emotional toll and acceptance
Blood Cancers & Disorders | Last Active: 6 hours ago | Replies (5)Comment receiving replies
@donna195
thanks for the good wishes. I never experience MGUS, just Smoldering. I have hand and foot numbness. Had it for years. Neurologist was the one who actually started the process. Abnormal nerve study. Blood work. And there you go. M proteins, Lambda, well it was a shock. Numbness to pre-cancer. I went to Rochester to start one of their clinical trials. 1q21.3 and 15% plasma cells in bone marrow was the only alert. All other blood work was on the low end. So Mayo criteria determined that its low probability. My story continues, so does everyone else. A collision course to destinies we can not control, but live with day in and day out.
Replies to "@donna195 thanks for the good wishes. I never experience MGUS, just Smoldering. I have hand and..."
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@msh466
So I have SMM IGA lambda. Low m proteins, low ratio, normal chemistries, no bone lesions. Just the 1q21.3 abnormality and 20% plasma cells in bone marrow. Where it gets fuzzy is all the criteria needed to establish what is what. Mayo uses this, my doctor uses the old standard. 1q21.3 is a high indicator that this will progress, while Mayo doesn’t. This wait and see is difficult. My reasoning is if it went from MGUS to SMM. What’s stopping it to go to the next level?