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@jeffmarc
Thank you Jeff, that's helpful. I was also trying to find a post where you had commented, that adding ARSI or APRI at the initial treatment (ADT + RT), helps in better control or probably in OS. I could be wrong...

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Replies to "@jeffmarc Thank you Jeff, that's helpful. I was also trying to find a post where you..."

@sbd
Adding an ARSI (ARPI is the same thing) when you are on ADT has been shown to greatly extend the amount of time it takes to become castrate resistant.

Median survival after becoming castrate resistant is two years. Happened to me six years ago.