Anyone taken Plaquenil (hydroxychloroquine) to reduce prednisone?

Posted by joancanzan @joancanzan, Aug 14, 2025

Has anyone taken hydroxychloroquine for prednisone reduction?

Interested in more discussions like this? Go to the Polymyalgia Rheumatica (PMR) Support Group.

Profile picture for mcarso @mcarso

I been taking HCQ for 2 years after tapering of prednisone. No side effects at all. Also I only had the flu once and only for 24 hours. I would like to know if statins drugs are related to PMR. I started statins also before PMR. Thanks

Jump to this post

After 7 months of prednisone, I began to experience Macular Degeneration. So my ophthalmologist suggested I switch to HCQ and the rheumatologist agreed. It worked. I slowly switched and then reduced the Hydroxychloroquine over a 2 year period.
PMR has now been in remission for two years.
I took statins for three years prior to getting PMR. And yes, I definitely believe statin drugs are related to PMR.

REPLY
Profile picture for hosers2 @hosers2

After 7 months of prednisone, I began to experience Macular Degeneration. So my ophthalmologist suggested I switch to HCQ and the rheumatologist agreed. It worked. I slowly switched and then reduced the Hydroxychloroquine over a 2 year period.
PMR has now been in remission for two years.
I took statins for three years prior to getting PMR. And yes, I definitely believe statin drugs are related to PMR.

Jump to this post

I believe the same; also I had 2 Covid shots prior to PMR. Are you still taking the statins? I’ll be taking to my Dr about this.

REPLY

Good luck with talking to your Dr. Most are pretty closed minded when it comes to statins. I know my Dr harasses me every time I see him. I am on a chat group called HealthUnlocked which is made up of PMR patients in the U.K. and Italy. One thing they all have in common is statins. (Most still take them, even though I told them what I think about statins.

REPLY
Profile picture for hammock117 @hammock117

Hydroxychloroquine plus methatrexate for several years helps reduce Lupus Flares. I try to stay away from predisone but I have it in case needed.

Jump to this post

REPLY

I am taking hydroxchloroquine and I just started methotrexate so far it has been working well. I didn’t want to take prednisone for my PMR. I am taking celebrex but hope to stop those.

REPLY

I take Methotrexate 2.5 Mg Tablet Take 6 Tablets By Mouth Once Weekly (Every 7 Days)
Hydroxychloroquine200 Mg Tablet - One Daily
and I am down to 2 mg of Prednisone daily to control my PMR.
I also take folic acid daily to fend off the side effect of the Mtehotrexate

REPLY
Please sign in or register to post a reply.