@bgpage My doc gave me low dose naltrexone...it took about 8 weeks for me to titrate up to 4.5 mg and now I have more energy, less fatigue, less food allergies, less shortness of breath, less palpitations, and all of the lesions on my legs have cleared up. The Naltrexone is regulating my overactive immune system. I will probably have to use it forever unless research finally finds something that is a cure...but I am better than I have been in 5 long years.

@bgpage
That's a pretty interesting link, and thank you for that.
I've subscribed to that theory as the most likely cause for decades, since I had that for about two years in the late eighties.
I'm very intrigued with its mention of Metformin as a possible aid in calming things down. It seems as though more information is coming out about that drug, making it something bordering on miraculous. In addition to controlling diabetes, some research indicates it may have anti-aging effects. It also, though, may decrease the benefits of exercise (which I can barely now do anyway), unfortunately.
My wife had a lot of trouble with her digestion with Metformin--a common side effect--but since there's a lot hanging around the house I just may experiment carefully with it to see if it does anything for my LC.
This is what we're reduced to, essentially, as LC/ME/CFS sufferers: throwing stuff at the wall, (harmless stuff, hopefully), and seeing what sticks!

In regards to nicotine--gum in my case--for LC. Like you, as a non-smoker, I expected a lot of effect, stimulation at least, but after gradually increasing the dose I rather oddly didn't feel any effects whatsoever.

@bgpage Super frustrating when medical professionals deny long-COVID's existence. They need to research Mayo Clinic's findings and many other respected institutions.