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How high should my Kappa light chain continue to rise before I worry.?
Blood Cancers & Disorders | Last Active: Jun 30 8:39am | Replies (29)Comment receiving replies
@kayabbott my recent kappa light chains is 26.3, lambda is 11 and ratio 2.39 and my Hematologist Oncologist at my local hospital wants to do Bone marrow test. But my numbers seem so low. What do u think. U give me hope.
Replies to "@kayabbott my recent kappa light chains is 26.3, lambda is 11 and ratio 2.39 and my..."
Hello! Somehow I found this post of yours from last year, so glad I did! It makes me feel better knowing I'm not asking for anything out of the ordinary for MGUS patients.
My numbers are just a bit higher than yours, I've practically begged for an initial bone marrow biopsy due to the MGUS, other bothersome symptoms, and the fact my brother had multiple myeloma and a sister had ALL which mutated into AML, but my local general oncologist (very qualified and professional, but not a hematologist even) said he wouldn't do a biopsy until my numbers rise dramatically!
Your post gave me inspiration to ask for a 2nd opinion and convince my primary doctor I'm not wanting to stop seeing my current oncologist, that I really like him and feel he's totally qualified, but I just want an MM specialist. Wishing you well on your journey!
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@barbarian1 I got a BMB soon after my MGUS diagnosis nine years ago, initial ratio was about 2.5. It was a baseline that showed the status of my various bone marrow cells. This added to info from my BMB this summer. The other main advantage of a baseline BMB is if they can run genetic tests that show your risk (elevated or low) of progression and of treatment options should your MGUS progess (hopefully never). My 2025 BMB plus bloodwork and lack of symptoms showed I am still at MGUS with a 1q21 mutation (chromosome 1, location 21 duplicated). BMB have no to minor pain and do give a lot of info to doctors.