@sams57 I recently was diagnosed with another problem that layered with PMR was difficult to find. Please follow your doctor's lead and work with them, yet express your concern. Tell every doctor you visit so they know, and ask them if they have concerns and can you watch for anything. Talk to your PCP about it. The PMR dosages and timelines are not normally seen by doctors to be the high dose, long term times they are concerned with. For some autoimmune problems they start at 60mg a day. One day at that level would be long term to me.