Looking for research re: taking AI drugs vs not taking them
I am currently taking Exemestane. I’m 61. Took a while but I’m doing well on it (doing yoga, pranayama and acupuncture). I now have osteopenia after taking it six months. I’m trying to find research on taking AIs vs not taking. What I’m finding there is not much difference between taking and not taking. But more likely to get arthritis and osteoporosis.
Can anyone post links. .
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I've mentioned this before. I'm now 84. I had a lumpectomy,chemo and radiation at age 79.I refused AI drugs. I see my oncologist every 6 months and he said that my blood tests show that I am in great health and no signs of cancer.
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7 ReactionsI'm thinking that I am not going to take it. I just started radiation last week. Reading everything thing I can about taking theses drugs before my appointment with the oncologist after the radiation is done. I'll be 80 soon and can't see how all the risks and side effects will help me in the next 10 years. My GP has encouraged me to try, but I don't think I am willing to risk bone loss and joint pain, and the other more serious side effects.
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7 ReactionsI certainly understand your decision and made the same decision 10 months ago. I am almost 70 and for the small percentage gains, not worth it at my age, with no guarantees. Everyone has different risk tolerance and at this stage of life, quality of life is pretty much everything! Good luck!!!
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7 ReactionsI’m 70, diagnosed with DCIS and maybe a tiny amount of IDC (depends on who you ask!)
I had a lumpectomy and targeted radiation, then had to wait 3 months for a Dexa scan to ensure that my mild osteopenia is stable. (It is).
I see the oncologist tomorrow and am still on the fence whether to take an aromatase inhibitor. I keep researching, and found that women who breastfed tend to have less aggressive BC and their tumors are less likely to return. I breastfed for 2 years total with my 2 kids. My tumor was 8 mm, ER+PR+ and I had no micro calcifications, it was seen by MRI. I was having a slight nipple discharge, and mammogram was negative, ultrasound negative, but MRI showed non mass enhancement. My chance of recurrence is 4-5% without endocrine therapy and 2-3% with it. Not sure that it’s worth it since I worry about heart disease, osteoporosis, etc. like everyone else. What if I don’t have bad side effects? This is really hard. I wish that I knew people that weren’t bothered by them all that much, but they seem to be outliers. If I was 50 or even 60, I’d give it a go, at 70, it doesn’t seem as necessary.
Anyone else heard of the breastfeeding link?
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3 Reactions@keywestsj Id agree with you - I’m 62- very low risk of reoccurrence and the side effects for me were pretty bad. I stuck with AIs a little over 2+ yrs joint aches and sleep issues. I may go back on after the holidays but for now, my joints feel like 62 not 100. Bless you.
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3 Reactions@ruffianfan55
Yes research show breasting feeding helps to protect you
@ruffianfan55
How did you get your numbers for chance of recurrence ? My oncologist just gives me estimates from general information because my IDC was also small like yours (mine 4 mm) and she would not do the Oncotype test since chemo would not be given.
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3 Reactions@ruffianfan55 I've heard that breast feeding your babies makes a big difference. Good luck and my God bless you in recovery.
@celestebradham
Hope that you can find some studies.
Please post. Try Pub Med.
I have quite a few stage 4 friends who said that the AI’s have kept them alive.
@raebaby
What stage and type of BC were you and are you doing and measures for your health?