i was diagnosed with osteoporosis at 55.....was prescribed biophosphonate tablets and vitD supplements....didnt work work...few months ago...i decided to change from osrtho to endocrinologist.....he performed a series to serum PTH test with a gap of 15 days to a month....it came out to be high and fluctuating.....the the doctor prescribe ultasound neck , which showed a nodule on parathyroid gland...to rule out cancer i was advised to take sestamibi scan of thyroid and parathyroid gland,...whcih came out negative.....m calcium levels were always normal....so the final diagnosis was normocalcemic hyperparathyroidism....which caused the osteoporosis......i am on alderonic acid(osteofos) and will be going ultrasound guided radiofrequency ablation to vaporise the abnormal gland.....that would most likely treat and hopefully cure the osteoporosis/boneloss..........if i would have taken HRT as advised by my orthopedc doctor...i would have lost more bone.