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Curious what medication to discuss with doctor regarding fibromyalgia

Posted by hudson757 @hudson757, Oct 13, 2025

I’ve had whole body pain most of my life but managed. Had back surgery in 2023 for sciatica pain. Got diagnosed with hoshimotos/hypothyroidism. Now just diagnosed in 2025 with fibromyalgia. I see a therapist and psychiatrist for cptsd and sorts. Had a nerve function test and it showed damage (failed surgery) carpal tunnel, nerve damage from head to toe. So the question is what’s a good medicine to start with for fibromyalgia? I’ve been on a couple of medications for pain. Not looking for medication with a dependence. Any suggestions I’d gladly take

Interested in more discussions like this? Go to the Fibromyalgia Support Group.

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ericamonique | @ericamonique | Nov 2, 2025

I was diagnosed with fibro many years ago. So, I've managed the pain with Duloxetine and pregabalin. But my pain has increased (old age?) so next week I'm starting on low dose naltrexone. It has no known side effects and apparently is very effective. I had to work to find a doctor who would prescribe it but I finally did. I'll let you know how it goes.

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memphismes | @memphismes | Nov 3, 2025
In reply to @ericamonique "I was diagnosed with fibro many years ago. So, I've managed the pain with Duloxetine and..." + (show)
Profile picture for ericamonique @ericamonique

I was diagnosed with fibro many years ago. So, I've managed the pain with Duloxetine and pregabalin. But my pain has increased (old age?) so next week I'm starting on low dose naltrexone. It has no known side effects and apparently is very effective. I had to work to find a doctor who would prescribe it but I finally did. I'll let you know how it goes.

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@ericamonique
Naltrexone is great. You have to give is 6 months to see the full effect. I got the best results taking 1.5 mg in the morning and night.

I have given my doctor the NIH article - https://pmc.ncbi.nlm.nih.gov/articles/PMC10039621/ to assist in their Naltrexone learning and get my prescription written.

I hope your pain is reduced.

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