@cdward1028 I posted my experience with Brinsupri I believe somewhere in this thread. I’ll summarize: after about 3 weeks on Brinsupri I developed increased phlegm, increased cough and did not feel well. Dropped off a sputum sample which showed inflammation (polys 4+) but no specific infection. No NTM, no pseudo. Pulmonary decided to treat me with abx and I’m feeling better. From my understanding it takes several months for Brinsupri to stabilize in your system. Does this help?