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@seeker001
You should do some research into the Patch study Which was a clinical trial that found that the estradiol patch worked as well as ADT and caused fewer hot flashes and less bone deterioration.

At least 50% of people using estradiol patches get gynecomastia, Though the average breast growth is not that much. It can be stopped if you get radiation to the chest before starting estrogen. Speak to a radiation oncologist about this.

If you have BRCA2, then you cannot use the estradiol patch. It greatly increases the chance of breast cancer, and people with BRCA2.

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Replies to "@seeker001 You should do some research into the Patch study Which was a clinical trial that..."

@jeffmarc Thank you for your helpful response. I already have moderate gynecomastia from ADT, and I don't really need any more. I will look into the radiation solution. I also will check BRCA2 and immerse myself in the PATCH study. I sense that good stuff is happening. Hope I live long enough to grab some of it.