Does anyone have a solution to help manage Reclast side effects?

@estelle17
Reminds me of one of the 2024 Shkreli award winners. I saw an expanded explanation last year but not now.

"Amgen’s Lumakras Pricing: The pharmaceutical giant was criticized for promoting a 960mg dose of its cancer drug Lumakras, despite evidence that a lower 240mg dose offered the same efficacy with fewer side effects. The higher dose costs $180,000 more per patient annually."

@estelle17
Reminds me of one of the 2024 Shkreli award winners. I saw an expanded explanation last year but not now.

"Amgen’s Lumakras Pricing: The pharmaceutical giant was criticized for promoting a 960mg dose of its cancer drug Lumakras, despite evidence that a lower 240mg dose offered the same efficacy with fewer side effects. The higher dose costs $180,000 more per patient annually."

@normahorn Thank you. She did not really give me an answer. I did read somewhere that there is no evidence that a half dose works. Still thinking of getting g another opinion before doing it.

@estelle17

Yes, there is evidence lower doses work.

I had my infusion a week ago. I have used ice with some success. My hands and wrists are swollen. No medical professional seems to have any answers.

@I did not have an endocrinologist from Mayo, I had one from the Medical College of Georgia. Of course they changed their name. They seem to do that every few years.
I am so sorry to hear of your multiple health issues. I would not take Prolia and I don't care who the doctor is or where they practice.
After my horrible experience with Reclast, I changed doctors and decided to not take meds. I hired a trainer and began lifting weights. My diet is a bone healthy one and I supplement with D3, K2, magnesium, Calcium, and a few others. Doctors make A lot of money prescribing these meds and I do not trust them at all. I have had no fractures and after two years of lifting weights, I can almost deadlift my body weight. It is my suggestion that you take a step back and educate yourself thoroughly and reassess where you are. It takes a lot of reading. I have multiple issues as do you and mine are different, but they could take me down if I were not so persistent. I hope you take a step back and ask God for guidance as you do your own research. You can be strong again.

@heartfelt70
Thank you for reply. I have educated myself thats why im terrified to take Reclast for Prolia the brittle bone drugs. I have had a fusion l4 l5 at mayo clinic may 1, 2025, supposed to do reclast feb 9. Have a mayo endo that i think will say oh no studies done on the sequence. I was on fosamax 5 years no gains, lost 2 % each dexa in spine. Do not want to be on bisph let alone an IV one that i can't stop taking and stays in my body for 10 years and gives horrible side effects. I have high blood pressure, osteoporosis, and COPD FOR 30 YEARS, SCARED TO DEATH, OF MY COPD IMMUNE RESPONSES I COULD HAVE RESPIRATORY FAILURE FROM THIS. I NEED TO FIND A MAYO ENDO WHO WILL BE WILLING TO TRY AFTER 2 MONTHS OFF OF EVENITY; A TRIAL OF 2 YEARS OF TERIPARTIDE OR TYMLOS. THINK MY INS WILL ONLY TRY TERIPARTIDE NOT TYMLOS. IT'S Aetna, regular medicare plan. do i just call them and explain my situation is all i can think of to do if i can't find on here anyone who has an Mayo rochester mn endo who put them on this sequence. i only have 4 months to figure this out. Dr. don't understand my risks are higher im terrified. They are not the ones getting this rock gut shit put in their bodies. Clinical trials are only for the healthiest people and then they get these dam drugs out in the real world with older people and people who have multiple other conditions that will worsen Reclast symptoms and we are supposed to blindly trust them. My surgeons said with my osteopenia and fusion only 6 or 7 months out, no stomping to improve bone density, can't lift over 10 lbs. what am i going to do. Need as normal bone as i can get, want to get out of osteopenia range and into normal range. Need more bone building as 5 years previous fosamax will blunt Evenity to maybe 9 % gains in spine not the 13.7 % in the clinical trials. Going to explain this to my endo at mayo next. he never answers my long portal messages. I don't really like him but i don't have much time to find any one else at mayo rochester which is 4 hours from us in little pocahontas iowa nw iowa. Town of 1500 people. I feel like im doomed to have to be on reclast. thank you for your kind reply. So hoping you could tell me you had endo from mayo who did this. I suppose i won't find anyone on here. i need them to just reply to me on MEssenger so i don't have to keep checking here all the time. Diana Nighswonger from pocahontas iowa. Thanks.

@heartfelt70
Thank you for reply. I have educated myself thats why im terrified to take Reclast for Prolia the brittle bone drugs. I have had a fusion l4 l5 at mayo clinic may 1, 2025, supposed to do reclast feb 9. Have a mayo endo that i think will say oh no studies done on the sequence. I was on fosamax 5 years no gains, lost 2 % each dexa in spine. Do not want to be on bisph let alone an IV one that i can't stop taking and stays in my body for 10 years and gives horrible side effects. I have high blood pressure, osteoporosis, and COPD FOR 30 YEARS, SCARED TO DEATH, OF MY COPD IMMUNE RESPONSES I COULD HAVE RESPIRATORY FAILURE FROM THIS. I NEED TO FIND A MAYO ENDO WHO WILL BE WILLING TO TRY AFTER 2 MONTHS OFF OF EVENITY; A TRIAL OF 2 YEARS OF TERIPARTIDE OR TYMLOS. THINK MY INS WILL ONLY TRY TERIPARTIDE NOT TYMLOS. IT'S Aetna, regular medicare plan. do i just call them and explain my situation is all i can think of to do if i can't find on here anyone who has an Mayo rochester mn endo who put them on this sequence. i only have 4 months to figure this out. Dr. don't understand my risks are higher im terrified. They are not the ones getting this rock gut shit put in their bodies. Clinical trials are only for the healthiest people and then they get these dam drugs out in the real world with older people and people who have multiple other conditions that will worsen Reclast symptoms and we are supposed to blindly trust them. My surgeons said with my osteopenia and fusion only 6 or 7 months out, no stomping to improve bone density, can't lift over 10 lbs. what am i going to do. Need as normal bone as i can get, want to get out of osteopenia range and into normal range. Need more bone building as 5 years previous fosamax will blunt Evenity to maybe 9 % gains in spine not the 13.7 % in the clinical trials. Going to explain this to my endo at mayo next. he never answers my long portal messages. I don't really like him but i don't have much time to find any one else at mayo rochester which is 4 hours from us in little pocahontas iowa nw iowa. Town of 1500 people. I feel like im doomed to have to be on reclast. thank you for your kind reply. So hoping you could tell me you had endo from mayo who did this. I suppose i won't find anyone on here. i need them to just reply to me on MEssenger so i don't have to keep checking here all the time. Diana Nighswonger from pocahontas iowa. Thanks.

@heartfelt70
Thank you for reply. I have educated myself thats why im terrified to take Reclast for Prolia the brittle bone drugs. I have had a fusion l4 l5 at mayo clinic may 1, 2025, supposed to do reclast feb 9. Have a mayo endo that i think will say oh no studies done on the sequence. I was on fosamax 5 years no gains, lost 2 % each dexa in spine. Do not want to be on bisph let alone an IV one that i can't stop taking and stays in my body for 10 years and gives horrible side effects. I have high blood pressure, osteoporosis, and COPD FOR 30 YEARS, SCARED TO DEATH, OF MY COPD IMMUNE RESPONSES I COULD HAVE RESPIRATORY FAILURE FROM THIS. I NEED TO FIND A MAYO ENDO WHO WILL BE WILLING TO TRY AFTER 2 MONTHS OFF OF EVENITY; A TRIAL OF 2 YEARS OF TERIPARTIDE OR TYMLOS. THINK MY INS WILL ONLY TRY TERIPARTIDE NOT TYMLOS. IT'S Aetna, regular medicare plan. do i just call them and explain my situation is all i can think of to do if i can't find on here anyone who has an Mayo rochester mn endo who put them on this sequence. i only have 4 months to figure this out. Dr. don't understand my risks are higher im terrified. They are not the ones getting this rock gut shit put in their bodies. Clinical trials are only for the healthiest people and then they get these dam drugs out in the real world with older people and people who have multiple other conditions that will worsen Reclast symptoms and we are supposed to blindly trust them. My surgeons said with my osteopenia and fusion only 6 or 7 months out, no stomping to improve bone density, can't lift over 10 lbs. what am i going to do. Need as normal bone as i can get, want to get out of osteopenia range and into normal range. Need more bone building as 5 years previous fosamax will blunt Evenity to maybe 9 % gains in spine not the 13.7 % in the clinical trials. Going to explain this to my endo at mayo next. he never answers my long portal messages. I don't really like him but i don't have much time to find any one else at mayo rochester which is 4 hours from us in little pocahontas iowa nw iowa. Town of 1500 people. I feel like im doomed to have to be on reclast. thank you for your kind reply. So hoping you could tell me you had endo from mayo who did this. I suppose i won't find anyone on here. i need them to just reply to me on MEssenger so i don't have to keep checking here all the time. Diana Nighswonger from pocahontas iowa. Thanks.