Yale study reports chronic symptoms after Covid vaccine.

Posted by searcher1 @searcher1, Feb 20 2:11pm

A small number of people report chronic symptoms after receiving COVID-19 shots. A new study provides clues for further research.

Some of the most common chronic symptoms of PVS include exercise intolerance, excessive fatigue, brain fog, insomnia, and dizziness. They develop shortly after vaccination, within a day or two, can become more severe in the days that follow, and persist over time.

Along with spike protein persistence, the researchers are assessing the contributions of autoimmunity, tissue damage, and Epstein-Barr Virus (EBV) reactivation.
https://news.yale.edu/2025/02/19/immune-markers-post-vaccination-syndrome-indicate-future-research-directions

Interested in more discussions like this? Go to the Post-COVID Recovery & COVID-19 Support Group.

Profile picture for sweetwater9 @sweetwater9

I hope they can remedy your fissure. A couple of stitches maybe? But it is a sensitive area to stitch.

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No suturing anal fissures. That would be a last resort. Many heal on their own. Talk to your doctor.

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I have had long covid for 2 years now. Both my heart doctor and regular doctor said no more vaccine or boosters for me...avoiding large groups of people too now.

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Profile picture for tls5alex @tls5alex

The truth is the vaccine I’m 💯 sure caused your symptoms tho the covid infection could have started you down the pathway and the vaccine finished the job. I can tell u I’m 💯 sure because I never had covid but literally 4 days after the first Pfizer vaccine I became suddenly ill. I mean, sudden onset vertigo, dizziness, internal tremor, head fullness buzzing sensation with tinnitus and I had difficulty talking, concentrating and profound life altering fatigue. 4.5 years later after 3 shots I now am dx with Lupus SLE; MECFS; POTS; Dysautinomia; PEM; Tachacardia, and who knows what will further develop as time goes on. In my case, I have no doubt that the vaccine caused autoimmune disease for me. Research has shown that Covid and the vaccine can cause autoimmune disease so for you it’s most likely both Covid and the vaccine are responsible for your illness. I would have your doctor send you for lab work to test your ANA and go from there……it took over 4 years to get my dx and I don’t understand why doctors aren’t flying in that the vaccine and covid impact a persons immune system so if they get sick and stay chronically sick they need to test for autoimmune…this isn’t rocket science 🙄. I wish you well.

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@tls5alex
Not sure if this will help...
10/19/2023 - Harlan Krumholz and Akiko Iwasaki (Rishi Shiah, Lilo Wu, and Adith Arun) discuss preliminary findings and answer questions from LISTEN participants. (Long Covid – Post-Vaccination Syndrome PVS)
https://medicine.yale.edu/ycci/listen-study/video/
The Yale LISTEN Study Town Hall: October 2023
I found this enlightening -
8:00 minute - Difference in Percent of Participants Experiencing Symptom (Long Covid – PVS post-vaccination syndrome)
Long Covid -
Memory problems, Changed sense of smell, Brain fog, Shortness of breath, Cough, Sore throat, Excessive fatigue, Difficulty speaking properly, Changed sense of taste, Fatigue, Congested or runny nose, Phantom smells, Runny nose, Phlegm in back of throat, Headache, Constant thirst, Night sweats, Hypersomnia, Confusion, Insomnia, Hair loss, Dry scalp or dandruff, Dizziness, Throat pain or discomfort, Postnasal drip, Exercise Intolerance, Wheezing, Swollen hands or feet, Cold/burning lung sensation, Changes in voice, Phantom tastes
PVS -
Loss of hearing, Suicidal thoughts, Feelings of impending doom, Palpitations, Tinnitus, Numbness, Internal vibration, Neuropathy, Burning sensations
(Note: other studies have similar and additional symptoms)

8/25/2025 - Immunologist: Hope for ME/CFS and post-Covid, research needed
https://science-apa-at.translate.goog/power-search/17729239753393598891
“At the International Congress of Immunology (IUIS) in Vienna, immunologist Akiko Iwasaki of Yale University (USA) expressed hope that treatment options can be found for at least some of those affected by conditions such as ME/CFS and long/post-COVID. In an APA interview, she emphasized that the causes must be addressed. She sharply rejected views that ME/CFS or post-COVID might not be somatic illnesses. “

I have been following Dr. Akiko Iwasaki ( Yale - Medicine - Immunology ) to see what else she finds - google her name for more information.

This one is also interesting -
12/11/2024 - Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(24)00438-4
Highlights
“ SARS-CoV-2 spike protein persists in the skull-meninges-brain axis in COVID-19 patients
Spike protein is sufficient to induce brain pathological and behavioral changes in mice
Spike protein enhances brain vulnerability and exacerbates neurological damage in mice
mRNA vaccines reduce, but do not eliminate, the spike burden. “
Graphical abstract very interest
https://www.cell.com/cms/10.1016/j.chom.2024.11.007/asset/2c765af6-4df2-4090-ba35-07f4e448f475/main.assets/fx1_lrg.jpg
It’s a journey, Best Wishes for Your Journey!
🍀

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The booster thread was removed - its important to have discussions related to the vaccines since there are studies related to them and LC. Everything should be on the table for discussion/research until LC is eradicated.

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Hi everyone,

I’ve been living with persistent, 24/7 dizziness for the past four years. It started subtly after a work trip to the USA in June 2022, and escalated dramatically during a second, longer stay from November 2022 to March 2023. About eight months before the first trip, I received two Pfizer COVID vaccine doses (no boosters). I’m not claiming causation—just sharing the timeline in case it resonates with others.

The dizziness is constant but becomes significantly more noticeable when I’m at home. While working—especially in high-focus environments like my studio—I don’t perceive it at all. It’s as if my brain overrides the sensation during deep engagement, but the moment I decompress, it returns.

I’ve tried various medications:

• Cindrid 25mg (Cinnarizine) helped initially, then lost effectiveness.
• Atenolol 100mg buffers my cardiovascular system well.
• Montelukast (Maclutek 10mg) helps with allergic symptoms.
• Magnesium glycinate supports vagal tone and calms things slightly.

I’ve also tracked my BP/HR arcs and noticed strong parasympathetic tone, occasional vagal surges, and mild nausea episodes. No clear vestibular damage, no hypotension, no bradycardia—just this persistent, destabilizing dizziness.

I miss my life before this. I’ve stayed functional, creative, and emotionally present, but I’d love to hear from anyone who’s experienced something similar. Whether it’s post-vaccine, post-travel, autonomic, vestibular, or something else entirely—any insights, protocols, or shared patterns would mean a lot.

Thanks for reading,
Werner

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Profile picture for wbeukes @wbeukes

Hi everyone,

I’ve been living with persistent, 24/7 dizziness for the past four years. It started subtly after a work trip to the USA in June 2022, and escalated dramatically during a second, longer stay from November 2022 to March 2023. About eight months before the first trip, I received two Pfizer COVID vaccine doses (no boosters). I’m not claiming causation—just sharing the timeline in case it resonates with others.

The dizziness is constant but becomes significantly more noticeable when I’m at home. While working—especially in high-focus environments like my studio—I don’t perceive it at all. It’s as if my brain overrides the sensation during deep engagement, but the moment I decompress, it returns.

I’ve tried various medications:

• Cindrid 25mg (Cinnarizine) helped initially, then lost effectiveness.
• Atenolol 100mg buffers my cardiovascular system well.
• Montelukast (Maclutek 10mg) helps with allergic symptoms.
• Magnesium glycinate supports vagal tone and calms things slightly.

I’ve also tracked my BP/HR arcs and noticed strong parasympathetic tone, occasional vagal surges, and mild nausea episodes. No clear vestibular damage, no hypotension, no bradycardia—just this persistent, destabilizing dizziness.

I miss my life before this. I’ve stayed functional, creative, and emotionally present, but I’d love to hear from anyone who’s experienced something similar. Whether it’s post-vaccine, post-travel, autonomic, vestibular, or something else entirely—any insights, protocols, or shared patterns would mean a lot.

Thanks for reading,
Werner

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@wbeukes hi there. I have written my story of vaccine injury on here. I was healthy up until 4 days after getting the first Pfizer shot I became dizzy/vertigo with blurred vision and a headache. Lost vision in my left eye for a short time. I was so dizzy I had to hold onto my husband to walk. I also immediately developed rash, extreme fatigue, difficulty talking, concentrating, I couldn’t work. Daily crashes with internal tremors and tinnitus. I have never been able to go for walks for long because the dizziness sets in immediately. I used to have a terrible time in grocery stores. I was dx with vestibular migraine and PPPD…but the physio for this did nothing for me. I knew they were missing the mark. Knew the doctors had no clue what was happening to me. I have been searching for answers and knew this sudden illness and dizziness was going to cause me harm long term. I was eventually dx with chronic fatigue syndrome with MCAS and POTS. I kept pushing for answers as new symptoms would develop and as of January I’ve been dx with Lupus SLE and possibly Sjogren’s. I know the vaccines triggered my illness and I know that COVID itself has caused Long Covid in others which I believe is the same Illness/same pathophysiology. I believe in your case the vaccine triggered this. Although I warned my parents to stop getting the Covid vaccine they continued getting the boosters despite seeing me become so obviously sick from them. They believe the doctors (which I did too) and now my 83 year old mom has the same dizziness and she’s struggling with it constantly. I would say I. The last year my dizziness has improved but I still struggle going for a walk which I avoid. Which is sad as I always enjoyed walking. I would avoid the vaccine and try not to get Covid. Also, maybe try a ganglion block injection in the neck. I have an internal tremor and it’s supposed to help with that too. My friend who had the same issue has had a few treatments of ganglion block and she said the internal tremors are basically gone. I am going to try it too. It might help with the dizziness. Good luck and trust me….your not alone in this 👌

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Profile picture for wbeukes @wbeukes

Hi everyone,

I’ve been living with persistent, 24/7 dizziness for the past four years. It started subtly after a work trip to the USA in June 2022, and escalated dramatically during a second, longer stay from November 2022 to March 2023. About eight months before the first trip, I received two Pfizer COVID vaccine doses (no boosters). I’m not claiming causation—just sharing the timeline in case it resonates with others.

The dizziness is constant but becomes significantly more noticeable when I’m at home. While working—especially in high-focus environments like my studio—I don’t perceive it at all. It’s as if my brain overrides the sensation during deep engagement, but the moment I decompress, it returns.

I’ve tried various medications:

• Cindrid 25mg (Cinnarizine) helped initially, then lost effectiveness.
• Atenolol 100mg buffers my cardiovascular system well.
• Montelukast (Maclutek 10mg) helps with allergic symptoms.
• Magnesium glycinate supports vagal tone and calms things slightly.

I’ve also tracked my BP/HR arcs and noticed strong parasympathetic tone, occasional vagal surges, and mild nausea episodes. No clear vestibular damage, no hypotension, no bradycardia—just this persistent, destabilizing dizziness.

I miss my life before this. I’ve stayed functional, creative, and emotionally present, but I’d love to hear from anyone who’s experienced something similar. Whether it’s post-vaccine, post-travel, autonomic, vestibular, or something else entirely—any insights, protocols, or shared patterns would mean a lot.

Thanks for reading,
Werner

Jump to this post

@wbeukes same here after the 2nd Covid vaccine from Pfizer.
Immediately had issues walking especially on left side. Constantly worse after 4’years. No doctor has an answer as to what happened or why. Lots of guesses. Quality of life after vaccine has dropped dramatically. Maybe safe for others but not here. After 2nd shot no boosters or anything. Taken and won’t take any covid shots.

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What’s interesting is today I squeezed fresh lemon in 500ML water, drank it, and the dizziness subsided.

Here’s what I found using Copilot everyday.

Why Lemon Water Might Have Helped

1. Hydration + Electrolyte Shift• 500ml of water alone can restore blood volume, improving cerebral perfusion and baroreflex stability.
• Lemon adds potassium and citrate, which may buffer mild acidosis or support vascular tone.

2. pH and Histamine Modulation• Lemon is acidic in taste but alkalinizing in the body, which may reduce histamine sensitivity or mast cell activation.
• If your dizziness has a histaminergic or inflammatory component, this could explain the relief.

3. Gastric and Glycemic Reset• Lemon water can stimulate digestion, stabilize blood sugar, and modulate vagal tone—especially after a glycemic dip or emotional load.

4. Parasympathetic Rebalancing• The act of drinking slowly, paired with lemon’s sensory profile, may have reset your autonomic loop—especially if you were in a vagal-sympathetic mismatch.

Editor's Note:
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Read more:
What is Generative AI? What does this mean on Mayo Clinic Connect? https://connect.mayoclinic.org/blog/about-connect/newsfeed-post/what-is-generative-ai-artificial-intelligence-what-does-this-mean-on-mayo-clinic-connect/

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