So sorry you've had severe reaction to Prolia shots. Researching and reading reviews from those who are presently or previously taken osteoporosis drugs I highly recommend for anyone considering taking them. One of the major issues I've had with the shots is that it is a long-lasting drug in your system, so if you do have concerning side-effects, it is going to take awhile before it is out of your system again. Good luck to you and hope things will get better for you soon.