@bjrhinos1
In 2010 I had surgery because they said I had a 3+4 Gleason. After surgery, it turned out it was a 4+3. 3 1/2 years later, my PSA started rising so they did salvage radiation. That lasted 2 1/2 years before my PSA started rising again, and I went on Lupron.

I have a genetic problem, BRCA2, Which is why it keeps coming back. Have you had genetic testing? That could be why your cancer keeps coming back and if it’s the same genetic issue, as I have, there is a drug specifically for it.

After four reoccurrences, I am now on Orgovyx And Nubeqa. It is kept my cancer undetectable for the last 23 months. I did have to have a metastasis in my spine, zapped a couple of years ago, The drugs seem to keep everything under control.

You can Get genetic testing to find out if it could be a factor. Does anybody else in your family have cancer? You can get it here for free, If you live in the USA,, takes 2 to 3 weeks to get the results and a genetic counselor will call you. They will send you a kit that you return in the mail. Don’t say you want your doctor involved or they will hold off sending the kit until they contact your doctor.

Prostatecancerpromise.org

While Pluvicto Works well for some people. It only works real well for 1/3 of people OK for 1/3 of people and not at all for 1/3 of people. Some genetic problems, cause it to not work well. It sounds like it didn’t work too well for you, But the amount of time it actually is effective is not that long for many people.