It is more complicated than I truly understand but by short circuiting the regular programming, it can lay in bone that doesn’t get eaten away right away by the normal process. But because if you stop The remodeling completely for long term, this can leave the bones brittle, this is why there is a two year time limit on some of these drugs. I also learned this is dose related, if you are receiving one every month it is a lot different than taking it every six months. I am speculating that maybe slowing down the osteoclasts but not stopping them completely is better. The other variable is the slowing of bone remodeling from age. Please talk to your doctor to get your specific recommendations. This is a complex problem with more complex risks and benefits than I can truly understand. I just wanted to give you the basics of how these drugs work. Please know that this is the incredibly simplified version that I was given at Mayo Clinic. If you have a chance to go to a Mayo, do it. They give you all the answers you need to be comfortable. We were there for my husband who has a complex disease and this one just one arm of our visit.

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