Anyone considered bilateral orchiectomy: Why or why not?
Been treated for metastatic prostate cancer for the past 11 years. 82 yo & had a total prostatectomy. Have been successfully treated with Lupron for the past 10 yrs and Zytiga added about a year ago. Considering a bilateral orchiectomy to be able to hopefully get off the Lupron/Ellegard (very painful option compared to Lupron)
Has anyone considered this option & if not, why?
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@frankn
Dear brother in Christ ,
Jesus Christ will be with you
Wish you a speedy recovery and good health
In prayers
George K Mathew
India
@ozzie51
Hey, how soon after the orchiectomy did you start with antiandrogen therapy to deal with the 5% testosterone produced by adrenal glands? And is that a long term therapy?
I am glad I did not do that because now I added additional ADT that would have been needed either way. then Chemo so unless there is some other reason for the removal. I say keep them around.
@rxharleydude
Yes eligard is like a mild bee bite and there is orgovix. I was told that removal is not the end all.
That is accurate information! It is not the “end all“! I’ve been kicking this can down the road now for 15 years now and have pretty much run out of viable options. Even chemo doesn’t work anymore. Currently checking out some new clinical drug trials being offered.
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1 ReactionNever fear my comrade in the fight against PC. There is still hope with pluvicto which I believe my doctor has on my list. It is a radioactive substance that can attach itself to the cancer cells and destroy them. Doesn't that sound like fun?
@duberdicus
Be aware of that works real well for 1/3 of people OK for 1/3 of people and not at all for 1/3 of people.
The benefit of Pluvicto lasts for about 18 months
There are genetic issues with Pluvicto
Somatic testing could be helpful before treatment to see if there are any of these genetic issues
RB1, PTen, TP53 are Pluvicto resistant
ATM & BRCA work better with Pluvicto
Nothing is perfect. I am sure my doctor will do what is best for me and we will discuss pros and cons of both chemo and Pluvicto therapy compared to where I am now. That is what I like about him.
@sbd
It was prescribed about 2-4 weeks after if i recall. Had a little difficulty getting it filled (ins approved pharmacy) but have been faithfully on it ever since.
My oncologist is VERY happy with the results.
Yes, long term.
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2 Reactions@sbd
Can share the reasons for MY decision if you like.