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Going off ADT after 3 years: How did you do after ADT?
Prostate Cancer | Last Active: Oct 21 4:16pm | Replies (23)Comment receiving replies
My husband is Gleason 9, Dechipher .99 (he is 82) and had radiation followed by 2 years of Zytiga + prednisone and Lupron depot. We are three months away from the end of the two year treatment. Three months ago they reduced my husbands dose of Zytiga to half (500mg) because he was having so many problems. We go to the Oncologist on Thursday and will see what his PSA is then. And of course what it will be after he finishes his regime in January. We are hoping.
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@ellen45
If his PSA is Rising ask the doctor to prescribe Darolutamide. I was on Zytiga for 2 1/2 years and in that time, my PSA was undetectable for only one month. It also caused me to have four Afib events with the last one landing me in the hospital for four days With a pulse of 175 standing. After getting off of it, I had to have a metastasis on my spine zapped, So it really wasn’t a great help.
My oncologist pulled me off and put me on Darolutamide And for the last 23 months, I’ve been undetectable. I am 78 in two weeks, And I’ve been on ADT for almost 9 years.
If you attend one of the ancan.org Advanced prostate cancer weekly meetings you will find that at least a dozen people there, most in their late 70’s and 80s are on Darolutamide. Many of them, taking it as they only drug.
The reason that drug is the drug of choice is because it has the least side effects and doesn’t pass the blood brain barrier, causing brain fog Like Zytiga does.