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PSA levels increase. When to be concerned?
Prostate Cancer | Last Active: Oct 27, 2025 | Replies (46)Comment receiving replies
Sept. 29 through Oct. 10 I had a bad UTI. My MD ordered a PSA, which I had done on Oct. 13, a few days after the UTI had run its course. My previous PSA (a year ago) was 1.4. My PSA from last week was 11.3. I was terrified.
I'm 64 and have a history of urinary strictures, a bladder diverticula, and probably an enlarged prostate. They made an appointment for me to see urologist next Monday. I could understand a UTI making PSA jump somewhat, but that much - 1100%?
Replies to "Sept. 29 through Oct. 10 I had a bad UTI. My MD ordered a PSA, which..."
@jimabassplayer
Had a friend who had a real big prostate and his PSA was always around 50. Multiple biopsies showed nothing.
As was also said, your PSA could be due to the UTI and prostate size. Get another PSA test in a few months. I can’t hurt to see a urologist to discuss what’s going on. Maybe you can get an MRI to see what’s happening, And if any tumors are visible.
@jimabassplayer I had a PSA of 4.8 in 2017. Urologist said let's wait and see what happens. PSA went from there to almost 10 and back down to 5 in 2 years. Then it stayed between 5 and 10 for 4 years. In the next year it hit almost 14. Biopsy was done and I had cancer. While waiting to start treatment, (my RO made me wait almost 4 months), my PSA spiked to 22. I had 28 sessions of radiation and I am 8 months done. My last PSA was 4.4. My point is your PSA can go up and down pretty fast and yours was a years difference so that is possible. It could be it is growing faster than normal but this stuff is unpredictable. Once it's over 10 probably a good idea to get a biopsy to see what's what. Good Luck.
@jimabassplayer
Question everything I do believe other things may make PSA levels rise. My PSA level started off at three then five then seven no nine and I have a slow growth cancer and I am on active surveillance had an MRI and I’m going for a fusion biopsy. please see if there is a medication that can lower your PSA or ask for a MRI before doing anything best of luck God bless peace
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@jimabassplayer -- I'm not a medical professional so take my layman opinion with a grain of salt. But I do believe a severe UTI can temporarily raise one's psa very significantly. PSA is a chemical mostly produced in the prostate, so any severe trauma or infection/inflammation to a non-cancerous prostate can cause a lot of psa to leak into the bloodstream. That said, you definitely want to follow up with the urologist and stay on top of it until it returns to normal. Prostate cancer is one disease where finding it early leaves one with many more options than finding it late. So even though your high psa might well just be from the severe UTI, you still need to follow your MD's advice and definitely follow-up with the urologist and get this figured out. Best wishes.