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DiscussionWhat's a good anti inflamation drug (not prednisone) for PMR?
Polymyalgia Rheumatica (PMR) | Last Active: Oct 21, 2025 | Replies (41)Comment receiving replies
Replies to "Has anyone’s Doctor prescribed Methotrexate? Supposedly an alternative to Prednisone"
@ddr
My rheumatologist has me in prednisone (I’m trying the 3.7mg drop from 4 mg) & methotrexate 15 mgs once a week. He’s saying get off pred & metho should take over. I have osteoporosis so getting off prednisone is very important for me. So far so good. Started prednisone March 2025 & metho in May 2025.
I do hear some folks say methotrexate doesn’t help them but I’m hoping I continue to improve! It’s been a not so fun year!!! I’d like to lose the weight & grow some hair!!!
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@ddr I'm now taking both prednisone and methotrezate. (as of today, 10 mg of prednisone and 7 1/2 methotrexate.) My rheumatologist is hoping the methotrexate will help wean me off the prednisone. I also have osteoporosis. I really have to get off the prednisone for all kinds of reasons--having a huge problem with hair loss is one of them. Good luck as you look for what works best for you!