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Prolia treatment for osteoporosis: What is your experience?
Osteoporosis & Bone Health | Last Active: Jul 13 3:27pm | Replies (1246)Comment receiving replies
My rheumatologist is very knowledgeable about drugs as she was a pharmacist before becoming a doctor. I was on teriparatide for two years and saw a large increase in bone density--i believe it usually increases the BMD in the spine more than the hip. I was on reclast for 3-4 years. My doctor then recommended prolia. She said that what she liked was that BMD continued to increase after stopping prolia.
I was diagnosed with severe osteoporosis at the age of 40--most likely due to use of steroid inhalers for my asthma. After 18 years of treatment with fosomax, teriparatide, reclast, and now prolia, I have finally progressed from severe osteoporosis to osteopenia. I am now 58. I am going to continue treatment as I do not want to have a broken hip at the age of 87 as my mother did. This is not a 2-3 year treatment that will fix everything. It's a long journey, and one that I'm willing to take to prevent spine compression fractures.
Replies to "My rheumatologist is very knowledgeable about drugs as she was a pharmacist before becoming a doctor...."
Thank you for sharing this. So wonderful that you are doing well.
Does Prolia leads to rebound fracture in the long run? Can one stop prolia after 5 years or stopping Prolia will again enhance breaking of bones in hips and spine?
@ritafarmer could you share the types of exercise regimen you are doing? Tia
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Prolia can cause rebound fracture if you stop prolia altogether. You will have to get addicted to Prolia forever if you do not want to break your bones like pack of cards. By googling I found that Prolia is less effective than bisphosphonates for reducing fractures and increases infection risk. Now Aclasta contains zolendronic acid (sometimes called zolendronate) and it belongs to bisphosphonates group. I think it is more effective than Prolia.
My mother Sobha Ghoshal has taken Bonmax Pth (teriparatide) injection for 2 years for Osteoporosis. But it failed to increase the bone density in the hips and so the risk of hip fracture is still there after completion of 2 years course. The T-score in the femur neck right as well as left in the hips did not improve at all from the first BMD Test done on 19.09.2018 although there is drastic improvement of bone density in AP Spine. Please see the chart below.
BMD TEST done on 19.09.2015
BMD Test Done on 18.09.2017
Region
T-Score
Region
T-Score
Femur Neck Left
-2.2
Femur Neck Left
-2.2
Femur Neck Right
-2.1
Femur Left Right
-1.8
AP Spine L1-L4 is 1.007 g/cm2
-2.2
AP Spine L1-L4 is 0.920 g/cm2
-1.4