I stopped taking Fosamax a few years ago after being on it and off it for about five years. The bone aches/cramps, and stomach distress were on-going throughout the time I took it. When media started reporting what research was finding out about Fosamax and other drugs to treat osteoporosis, I stopped taking it. My doctor recommends I try another drug in this class, but until the safety and long-term effectiveness of a drug can be better assured - I will not be taking any of them. I feel 100% better since stopping Fosamax.