@pmm
Will certainly keep you posted. My lambda free light chains have escalated with each of my four joint replacement surgeries. They do ebb afterward but not as much as I would think - and want.
My hip replacement surgery was delayed cause of Covid - it was considered an elective surgery until they saw the xrays where the femur had actually broken off and I had avascular necrosis. I was in unbelievable pain, screaming whenever I walked five feet. It was a successful easy surgery with no pain whatsoever - neither post operatively or longer term. I was walking normally without a walker three days later. The free light chains decreased a whole after this surgery.
The shoulder replacement surgery under general anesthesia (the rest were regional anesthesia) escalated my lambda flc the most (. They have come down (270-220) but are still too high.
I do not know if these flc are all monoclonal or if there could be inflammatory polyclonal chains measured in there also. My hematologist insists they are monoclonal but I would like this tested. My husband is suspicious that the joint protheses interactions with my immune system could be a factor.
All my other chemistries and blood counts are stellar. There is no sign of anemia - quite the contrary. So I don’t know. I would like my polyclonal hypothesis checked out.