MGUS and GLP-1’s

Posted by amyboylan1 @amyboylan1, Oct 13 4:35pm

Hi,
I was diagnosed with MGUS in 2024. I have done some research and have found that a BMI in the normal range is suggested to help keep the MGUS from progressing. I very much want to get my BMI in the normal range. I am currently in the overweight range. I was wondering if anyone is on or have tried the GLP -1’s like ozempic? I would like to get my weight down as soon as i can and this could help me with this goal. My oncologist could not advise me. If anyone is on one, has it affected your numbers? I would be grateful for any responses. Thanks!

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2121 | @leslie2121 | Oct 14 3:23pm

I was diagnosed in 2021 and am also overweight- have increased exercise but weight is stubborn- still want to lose 20 lbs.
I have been stable mgus-wise where it is undetectable but want to do all I can to be healthy.
So also interested in your question.

kayabbott | @kayabbott | Oct 15 8:01am

I found some interesting research on GLP-1 meds and MGUS progression, at least for people that are type 2 diabetic. The research is early stage. https://pmc.ncbi.nlm.nih.gov/articles/PMC11643351/ https://ascopubs.org/doi/10.1200/JCO.2025.43.16_suppl.7559

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