@ucfron @wingnut

When it comes to supplements, most work will be your own. NIH had the office of alternative medicine, at one time anyway back some decades, which mostly got closed the last 20 years till now they just make a few pamphlets. Something along the lines of an "NIH complimentary medicine institute" would be needed, and well it doesn't exist.

My primary care did regular medicine for a few decades but switched to "holistic" primary care and charges outside medicare coding for help in these areas. You can find some other doctors like that. But and I will say one has to be very careful. In the prostate there is too much focus on 5-alpha reductase inhibitors and these are available as prescriptions (dutasteride and finasteride) and the prescriptions work better than OTC products aimed at the same method of action.

So one is left to look on their own, and if you are looking for anti-cancer properties well just know that 5-alpha reductase inhibitors don't do that as an endpoint. So that eliminates much of what is sold for prostates OTC or prescription. I focused a lot on going around the 5-alpha reductase inhibitors trap that most supplement sellers focus on in prostate supplements, plus what I could easily take and not negatively impact my liver enzymes and so on. So I do a lot on my own, and if interested learning on your own then realize most things sold are just 5-alpha reductase inhibitors which you are better off getting a prescription for one if that is the method of action you want.

So anyway that is how I worked it, but others also found what I found, most of these things work on Gleason 3 but they have a harder time working on Gleason 4 cells. Maybe if an "NIH complimentary medicine institute" studied and gave grants for effects on Gleason 4 cells we could get somewhere with supplements and PCa but you won't find that just yet. The future has these possibilities but no time soon anyway.

So mostly one is on their own is the long and short of that, but watch the liver for negative impacts, tell all your doctors what you take, and if you have any holistic doctor in your area it might help.